Development and Validation of a Health Policy Simulation Model for Cardiovascular Disease

Relative contribution of trends in myocardial infarction event rates and case fatality to declines in mortality: an international comparative study of 1·95 million events in 80·4 million people in four countries

X Camacho, L Nedkoff, FL Wright, N Nghiem, E Buajitti, R Goldacre, LC Rosella, O Seminog, EJ Tan, A Hayes, A Hayen, N Wilson, T Blakely, P Clarke

2022-03-01

Background: Myocardial infarction mortality has declined since the 1970s, but contemporary drivers of this trend remain unexplaine..

Estimating risk factor progression equations for the UKPDS Outcomes Model 2 (UKPDS 90)

J Leal, M Alva, V Gregory, A Hayes, B Mihaylova, AM Gray, RR Holman, P Clarke

2021-10-01

Objectives: To estimate 13 equations that predict clinically plausible risk factor time paths to inform the United Kingdom Prospec..

Trends in Ischaemic Heart Disease in Australia, 2001–2015: A Comparison of Urban and Rural Populations

EJ Tan, A Hayen, P Clarke, R Jackson, J Knight, AJ Hayes

2021-07-01

Objective: Ischaemic heart disease (IHD) is a major source of disease burden worldwide. Recent trends show incidence is declining ..

Self-rated health scores predict mortality among people with type 2 diabetes differently across three different country groupings: findings from the ADVANCE and ADVANCE-ON trials

X Hua, TWC Lung, M Woodward, JA Salomon, P Hamet, SB Harrap, G Mancia, N Poulter, J Chalmers, PM Clarke

2020-08-01

Aims: To explore whether there is a different strength of association between self-rated health and all-cause mortality in people ..

Health system costs for individual and comorbid noncommunicable diseases: An analysis of publicly funded health events from New Zealand

Tony Blakely, Giorgi Kvizhinadze, June Atkinson, Joseph Dieleman, Philip Clarke

2019-01-01

Background There is little systematic assessment of how total health expenditure is distributed across diseases and comorbidities...

Australian general practitioners initiate statin therapy primarily on the basis of lipid levels; New Zealand general practitioners use absolute risk

C Schilling, J Knight, D Mortimer, D Petrie, P Clarke, J Chalmers, A Kerr, R Jackson

2017-12-01

Objectives To compare the determinants of initial statin prescribing between New Zealand and Australia. New Zealand has a system-w..

How Consistent is the Relationship between Improved Glucose Control and Modelled Health Outcomes for People with Type 2 Diabetes Mellitus? a Systematic Review

X Hua, TWC Lung, A Palmer, L Si, WH Herman, P Clarke

2017-03-01

Background: There are an increasing number of studies using simulation models to conduct cost-effectiveness analyses for type 2 di..

Revisiting the "Christmas Holiday Effect" in the Southern Hemisphere

J Knight, C Schilling, A Barnett, R Jackson, P Clarke

2016-12-01

Background--A "Christmas holiday effect" showing elevated cardiovascular mortality over the Christmas holidays (December 25 to Jan..

Using Classification and Regression Trees (CART) to Identify Prescribing Thresholds for Cardiovascular Disease

C Schilling, D Mortimer, K Dalziel, E Heeley, J Chalmers, P Clarke

2016-02-01

Background and Objective: Many guidelines for clinical decisions are hierarchical and nonlinear. Evaluating if these guidelines ar..